Elevated DNA fragmentation is linked with infertility and miscarriage. Men with an abnormal semen analysis may have increased DNA fragmentation also. https://www.infertilityaide.com/blog/sperm-dna-fragmentation-testing So, to sum up, the higher the sperm DNA damage index, the … The results obtained with CANfrag are consistent and reliable. The valuable and intellectual afford of our team made the kit, easy to perform and score. CANfrag DNA fragmentation Test kit is designed to detect DNA fragmentation in human sperm. • Low sperm DNA damage means that the quality of the sperm is good. • High sperm DNA damage means the quality of sperm is poor. DNA fragmentation was last discussed at the October 2018 SCAAC meeting. Sperm carries DNA from the male testicles to the female egg. UNDERSTANDING THE REASON FOR SPERM DNA FRAGMENTATION TESTING. It is important that this DNA is of optimum quality to ensure the healthy development of the embryo and foetus. All men have some amount of damage to their sperm DNA, but high percentages of damage may indicate greater difficulty achieving pregnancy with IUI and IVF. Sperm deliver paternal DNA to the egg during fertilization. Sperm DNA fragmentation is less often tested—and generally less well understood—than other semen parameters and sperm quality measures, such as sperm count, motility, and morphology. For trying-to-conceive (TTC) couples and their doctors, the SCSA test is the original and Gold Standard for sperm DNA fragmentation screening that delivers a highly accurate measure of male reproductive health. Each sperm has two strands of DNA. Sperm DNA fragmentation testing is an opportunity to evaluate male fertility beyond semen analysis for those undergoing infertility treatments. DNA Fragmentation Test . The Exact test result shows three different indicators of DNA damage (fragmentation) compared against a fertile reference range. The improved SCD test, developed as the Halosperm kit, is a simple, cost effective, rapid, reliable, and accurate procedure, for routinely assessing human sperm DNA fragmentation in the clinical andrology laboratory. DNA fragmentation testing is a type of male fertility test which measures the amount of damaged DNA in a sperm sample. The results of a sperm DNA damage test are unlikely to impact on the management of your treatment. This is SCD test based kit. Sperm DNA fragmentation refers to the presence of sperm with damaged (broken) DNA, which affects male fertility.. Alterations of any kind in sperm DNA are likely to cause infertility in the man affected, as integrity of sperm DNA is key to obtaining viable embryos and subsequently a healthy baby.. Fragmentation occurs when one or both of these strands become damaged or broken. Minutes of the October 2018 discussion and the evidence used to inform this discussion are available here . The sperm DNA fragmentation test can help determine a couple’s chance for a successful pregnancy based on the health of a man’s sperm. Sperm DNA fragmentation can also improve the success of IVF. What Is Sperm DNA Fragmentation?