Following removal of the suture, each side was randomly treated with either topical onion extract or petroleum jelly. The products were applied twice daily for two months following suture removal. 4.0 out of 5 stars331. Of the patients who used onion extract gel (n=43), 11 patients (25.6%) reported significant local reaction (itching, burning, redness). The scores for the five different parameters and the VAS were calculated and compared. Detection of Angiotensin II and AT1 Receptor Concentrations in Keloid and Hypertrophic Scar, Split-face Evaluation of a Multi-ingredient Brightening Foam Versus a Reference Control in Women with Photodamaged Facial Skin, Diseases that impair wound healing, such as diabetes mellitus and connective tissue diseases. Place the beaker in a water bath at 140 degrees Fahrenheit for 15 minutes. Onion extract gel is an effective remedy for the treatment of keloids. Alternatively, you can soak a … Clarke LF, Baker B, Trahan C, et al. ©2020 JCAD | The Journal of Clinical and Aesthetic Dermatology. Rub the whole onion against the fine side of the grater. The first 15 people will be treated with a gel containing onion extract, allantoin and pentaglycan, 2 times a day for 24. ABSTRACT: Objectives.Topical onion extract gel is commonly used in commercial anti-scar medications. Chanprapaph K, Tanrattanakorn S, Wattanakrai P, et al. The resulting substance appears in some types of skin medications and lotions to treat and reduce the appearance of acne and scars. Update on scar management: guidelines for treating Asian patients. It seems we may be in another round of marketing hype promoting use of an onion extract gel to reduce scars so they heal less obviously than without it. 2006;32(7):891–896. All patients had additional follow-up appointments in the eighth postoperative week and were evaluated objectively by two observers: an oculoplastic surgeon and an ophthalmologist, who were blind to the type of medications. An indicator that the gel is ready to be loaded is that there will be resistance while carefully pulling the toe spacers out of the soap dish. A new quantitative scale for clinical scar assessment. Dip a cotton ball in an onion juice and apply it … Silicone sheets can be washed and reused. Design. If these symptoms appear after using onion extract or a product that contains it, stop use and contact your dermatologist. The gel from this tropical plant can help reduce inflammation and improve healing of burn wounds, says the Memorial Sloane Kettering Cancer Center. Transfer the beaker to an ice water bath for five minutes and stir often. We also make onion hair oil and use it as a pre-shampoo treatment to treat scalp problems. Current methods employed in the prevention and minimization of surgical scars. Check with your dermatologist before applying onion extract to your skin. Results from clinical studies on surgical scars in Caucasians were disappointing. The exclusion criteria of our study included the following: Blepharoplasty was done by an oculoplastic surgeon under standby anesthesia (lidocaine 2% with 1/100,000 epinephrine), and incisions were closed with continuous 6/0 nylon sutures. Evidence-based scar management: how to improve results with technique and technology. Topical onion extract gel was ineffective in improving overall blepharoplasty scar appearance when compared with a petroleum-based ointment. If these items seem to improve your acne or fade a scar, onion extract may be the reason. Beuth J, Hunzelmann N, Van Leendert R, et al. You can also get this thing wear they take a patch ofs skin and put the top layer over a certain area. Our study investigated two topical agents in a single patient simultaneously. The purpose of this study was to evaluate the effectiveness of topical onion extract gel on the appearance of blepharoplasty scars and to compare the results of its use to those of petroleum jelly. The observers used the Manchester Scar Scale (MSS).6 The MSS evaluates the following five characteristics of scar: color (score: 1–4), distortion (score: 1–4), contour (score: 1–4), texture (score: 1–4), and transparency (score: 1–2) (Table 1). If you have sensitive skin, straight onion extract may result in a reaction. Grab the rounded end of the onion, if left intact, with your free hand. A moist environment is considered essential in wound healing, especially in chronic cases.13 A humidified setting accelerates cutaneous wound healing and prevents scars, which could be achieved by petroleum jelly.14,15. Leave on hair and scalp for 30 minutes. Put onion cubes in a food processor and grind it to make a fine paste. Hosnuter et al17 demonstrated no significant influence of onion extract gel on the height, itching, or color of hypertrophic and keloid scars. Black EH NF, Gladstone G, Levine MR, Calvano CJ. Onion extract gel is available in both Europe and the United States. Did you find this post helpful? Results of a multicenter, comparative epidemiological cohort study in Germany. Onion extract gel (Contractubex™; Merz Pharma, Frankfurt, Germany) From the day of suture removal, the treatment was applied three times daily for 3 months. Participants.Out of 43 participants who had upper blepharoplasty, 26 patients completed the follow up. Now, put an onion quarter inside the chute of the juicer and turn the device on. Draelos ZD. Onion extract is formed by breaking down the flesh of an onion. Some research indicates that onion extract is beneficial for acne and scars because it has anti-inflammatory and antimicrobial properties. Extract the juice and add few drops of rosemary essential oil. There was neither a statistically significant difference in any of the scar characteristics (color, translucence, contour, distortion, and texture [all had p-value <0.05]) nor in the sum of the scores. Most research suggests that applying onion extract, usually as a specific product containing heparin and allantoin (Contractubex), to the skin for 10 weeks to 6 months improves scar color and appearance, as well as pain and itching, in people with scars due to burns, tattoo removal, injuries, or surgical removement of tissue. 5 The primary component in onions is quercetin, a flavonoid known for its potent biological effects. Sawada Y, Sone K. Hydration and occlusion treatment for hypertrophic scars and keloids. On the other hand, wound massage with physical manipulation of the scar at the earliest stage of wound remodeling (two weeks after wounding) can be beneficial.26,27 In our cases, the combination of physical massage with petroleum jelly or onion extract gel might have been bene?cial in improving the appearance of scars. 3 According to a literature review, there have been a few randomized, controlled trials conducted on the potential benefits of this topical onion extract gel product; 8 however, to our knowledge, our investigation is the first randomized, prospective, double-blinded study to evaluate the effectiveness of … However, using a specific product containing onion exract and allantoin (Mederma, Merz Pharmaceuticals) for 4-11 weeks does not seem to improve … Silicone Gel Sheeting. Background . Try a silicon jel sheet, medora, bio oil or other scar reducing creams, lotions, and jels. Effect of quercetin on the growth of mouse fibroblast cells. // Leaf Group Lifestyle, How to Make Homemade Stretch Mark Removal Cream, Metric Conversions.org: Cubic Centimeters to Ounces, National Weather Service Forecast Office: Fahrenheit to Celsius Converter. A few studies comparing the effects of onion extract gel (e.g., Erasé® gel [Zenta Healthcare, New Delhi, India] and Contractubex®) on the incision site from caesarean section found onion extract to be effective for scar reduction.21,22 Onion extract gel was also useful in scar treatment after thoracic surgery.23. RALEIGH, N.C. – A new once-daily topical gel containing a proprietary onion extract resulted in a 36% improvement in the appearance of recent postsurgical dermal scars at 8 weeks, according to the results of a randomized, controlled trial. Copyright © 2021 Leaf Group Ltd., all rights reserved. Results. Saulis et al18 found that onion extract gel was ineffective in the reduction of redness and scar hypertrophy in an induced rabbit ear wound. Safety and efficacy of local administration of contractubex to hypertrophic scars in comparison to corticosteroid treatment. Khansa I, Harrison B, Janis JE. J Clin Aesthet Dermatol. Blepharoplasty is one of the most common aesthetic surgeries in the world.1 Hypertrophic scars and keloids seldom occur around the eyelids.2 Since scars at the incision sites can present functional and aesthetic dilemmas and cause psychological stress in the patient, scar prevention is a concern for cosmetic surgeons. KEYWORDS: Blepharoplasty, Contractubex, scar, petroleum jelly. To properly prepare onion extract, you’ll need: Cutting board Knife Dish soap Water Ice Thermometer Coffee filters Distilled water Salt 2 medium-sized bowls Use of onion extract, heparin, allantoin gel in prevention of scarring in Chinese patients having laser removal of tattoos: a prospective randomized controlled trial. Foo CW, Tristani-Firouzi P. Topical modalities for treatment and prevention of postsurgical hypertrophic scars. Drs. A visual analogue scale (VAS) was also used, which scores the overall scar appearance on a scale of 0 to 10, where 10 denotes the worst appearance. A prospective double-blinded study of Mederma skin care versus placebo for post-traumatic scar reduction. Cut the dried onion into end-to-end quarters using a sharp knife. Roques C. Massage applied to scars. Move the onion … On the eyelid that received petroleum jelly, no local adverse reactions were reported. Additionally, Clarke et al19 found no difference in physician assessment of scar improvement between placebo and onion extract gel, while Chung et al20 evaluated the effects of onion extract gel in 24 subjects with new surgical wounds compared with petroleum ointment and found no statistically signi?cant di?erence in terms of scar symptoms, erythema, hypertrophy, and overall cosmetic improvement. Wound healing involves four different phases that overlap with each other: hemostasis, inflammation, proliferation, and maturation/remodeling.7 Disruption of the normal healing process leads to abnormal wound healing and scar formation.7. Onion extract and quercetin induce matrix metalloproteinase-1, Pawlikowska-Pawlega B, Gawron A. Can I Substitute Ground Fenugreek for ... How to Find a Telephone Number in New ... Eliza Martinez has written for print and online publications. Twenty Asians who had new Pfannenstiel’s cesarean … Wound repair and regeneration. All Rights Reserved. Patients and observers were blind to which medications were applied. Step 2: Apply cocoa butter Massage cocoa butter into the … • Onion extract gel • A dermatologist. Each participant was given two opaque drug canisters in accordance with the allocated group and instructed to apply one medication to the right eyelid and the other medication to the left eyelid two times a day for two months in combination with wound line massage. Based on our results, we found no difference between onion extract gel and petroleum jelly regarding their effects on scar appearance on the eyelids following blepharoplasty. Mix 3 grams of salt with about 1/3 ounce of liquid dish soap. Ocampo-Candiani J, Vazquez-Martinez OT, Iglesias Benavides JL, et al. Made Petroleum jelly is considerably cheaper than onion extract gel, and localized irritation was rarely reported with petroleum jelly. Onion extract (Allium cepa) is an active ingredient of many over-the-counter herbal products for scar treatment (e.g., Mederma®). These two agents, in addition to their direct effects on wound healing, might have acted as a lubricant for massage therapy. The mean MSS scores were was 10.076 for the side of the face that received the topical onion extract gel and 10.038 for the side that received petroleum jelly. Retinoid use within three months berfore the surgery. Liu A, Moy RL, Ozog DM. Try adding onion extract to your regular lotion or apply it directly to the problem areas. Dermatology Consulting Services, High Point, NC. A comparison of topical agents in the same individual eliminates intrinsic and extrinsic confounding factors that might affect scar formation. The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. Chung VQ, Kelley L, Marra D, Jiang SB. During the sixth-month phone follow-up, our patients were asked about their satisfaction levels when comparing their two eyelids and whether they perceived a difference in the appearance between the two eyelids. All patients were questioned about redness and the subjective appearance of scar between the two eyelids. Aloe Vera – People most commonly apply Aloe Vera gel to the skin in order to treat sunburns, burns, infections, cuts and other wounds. Onion extracts have been shown in vitro to accelerate wound healing. The study protocol conformed to the ethical guidelines of the 1975 Declaration of Helsinki. The topical onion extract gel used in the study is a top-selling over-the-counter antiscar agent. Pour the onion mixture into a blender and blend on high for five seconds. It is very beneficial because it acts as an analgesic and fights inflammation and itching. According to our results obtained using the MSS, the onion extract gel was equally effective as petroleum jelly in improving scar cosmesis following upper eyelid blepharoplasty. This in vivo study was conducted to evaluate the clinical effect of a topical gel containing onion extract, allantoin, and pentaglycan on hypertrophic scars and keloids. Patients were instructed to apply a cold compress for 20 minutes every two hours for 48 hours post-surgery. 6 Research has revealed that the quercetin in onion, which is a powerful antioxidant, inhibits collagen production and helps lower the incidence of keloids. Ebanel Advanced Silicone Scar Gel, Scar Removal Cream for Old & New Scars of Acne, Surgical, C-Section, Injuries, Burn, Cuts, Insect Bites, Stretch Marks with Vitamin E, Emu Oil, Onion Extract. Over time, silicone can fade the appearance of scars. Buy amazing onion extract gel on Alibaba.com at irresistible offers and enhance your well-being. The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. 3 Extensive research on scarring suggests that when used by themselves quercetin-containing creams may be far more effective at preventing scars, however, than in treating … 2. She covers a variety of topics, including parenting, nutrition, mental health, gardening, food and crafts. Rinse and use a mild shampoo to reduce any onion smells. All parameters of the MSS mentioned were scored for each eyelid and compared between sides. The observed side effects might be attributed to the constituting ingredients of onion extract gel and have been reported in other studies.28,29. Onion extract gel. The risk of abnormal scar tissue formation is higher in some parts of the body following a surgical wound (e.g., the shoulder, scapula, anterior chest, lower abdomen, earlobe, and all cutaneous tissues on bony prominences).24 In the studies that showed reduced scar formation after using onion extract gel following caesarean section and thoracic surgery, the results might be due to the higher potential for abnormal scar formation in the studied surgical sites than in our studied surgical site, the eyelid, which has a lower risk for this type of scar. Beausang E, Floyd H, Dunn KW, et al. The surgical sites were allowed to heal for 2 to 3 weeks, at which time the subjects returned to the research center for randomization to either the onion gel treatment group or the no‐treatment group. Willital G, Heine H. Efficacy of Contractubex gel in the treatment of fresh scars after thoracic surgery in children and adolescents. Despite these studies, evidence on onion extract is mixed. Morganroth P, Wilmot AC, Miller C. Over-the-counter scar products for postsurgical patients: disparities between online advertised benefits and evidence regarding efficacy. Cho JW, Cho SY, Lee SR, Lee KS. Conclusion. On this basis, it can be assumed that the oil prepared from onion extracts can help in nourishing the skin. Patients also applied topical erythromycin eye ointment twice daily until suture removal at one-week post-surgery. Owji, Khademi, and Khalili are with the Poostchi Ophthalmology Research Center at the Shiraz University of Medical Sciences in Shiraz, Iran. Onion extract is an ingredient in many skin care products. $15.99$15.99($14.28/Fl Oz) $14.39 with Subscribe & … The scores for the five different parameters and the VAS were calculated and compared with each other. Six months after surgery, a follow-up phone interview was conducted. Ho WS, Ying SY, Chan PC, Chan HH. We apply onion juice directly on the scalp to treat certain scalp infections. These factors and the results of our study suggest petroleum jelly is a suitable option for post-blepharoplasty wound care. Gathering all your materials in one place prior to beginning the process of making onion extract makes it quicker and more efficient. The ages of the patients ranged from 39 to 65 years, with an average age of 51.5 years. People who used an onion extract gel reported improvements in scar texture, softness, redness, and overall appearance after 4 weeks. Perhaps its role occurs through its antibacterial, anti-inflammatory, antiproliferative, and collagen downregulatory properties. The topical onion extract gel used in the study is a top-selling over-the-counter antiscar agent.3 According to a literature review, there have been a few randomized, controlled trials conducted on the potential benefits of this topical onion extract gel product;8 however, to our knowledge, our investigation is the first randomized, prospective, double-blinded study to evaluate the effectiveness of this topical agent for the improvement of scarring after blepharoplasty. There was no statistically signi?cant di?erence in overall cosmetic appearance objectively and/or subjectively between the two sides (p value: 0.25). The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. Perform clinical evaluation and … This is a … Transfer the beaker to an ice water bath for five minutes and stir often. We extract the onion juice by pounding the small onions in a mortar and pestle and then take the pounded paste in a strainer and press with a spoon to extract the juice. Creating onion extract is simple and economical, and doing so at home allows you to use the quantity you prefer. Onion is a plant. The gel should be poured to a 0.5 cm thickness. Background: The development of hypertrophic scars after burns can lead to esthetic as well as functional disorders. Jackson BA, Shelton AJ. Mederma®, the American formulation of topical onion extract gel (Merz North America, Raleigh, North Carolina) contains 10% aqueous onion extract and 1% allantoin. Patients/Methods . The effects of onion extract on hypertrophic and keloid scars. Of the 43 subjects who were included in the study, 26 patients completed the follow-up. The bulb (rounded underground part) of the onion is used to make medicine. Skin: histology and physiology of wound healing. The proven health benefits of onion extract gel will leave you with a smile. The foam should stay on the coffee filter while the onion extract flows into the beaker. Our study is limited by the small sample size. Seven subjects did not complete the study due to incomplete follow-up. Liquid dish soap, water, ice, a thermometer, coffee filters, distilled water, sodium chloride, also known as table salt, and two beakers or other containers that hold at least 8.5 ounces are additional pieces of equipment needed. Kim S, Choi TH, Liu W, et al. JCAD | The Journal of Clinical and Aesthetic Dermatology. Setting.The study was carried out in the Khalili and Dastghaib Hospitals in Shiraz, Iran. Sutures were removed on the seventh postoperative day. When we evaluated the safety profile of these medications, we enrolled all patients, including those who left the study. Patients were also questioned about any difference in scar redness between the two lids; the results showed no difference (p-value: 0.793). Mederma® Cream by Win Medicare has only natural but still potent and effective healing, scar removal, and skin lightening ingredients – Allium Cepa Onion Extract 0.05%. The study showed that the onion extract gel significantly improved scar softness, redness, texture, and global appearance at the excision site at study weeks 4, 6, and 10 as assessed by the blinded investigator. To the best of our knowledge, this is the first study to investigate the efficacy of topical onion extract for the improvement of blepharoplasty scars. Subjects returned to the study center at weeks 2, 4, 6, and 10 for photography, subject evaluations, and investigator assessments. Our results agree with previous studies. Field CK, Kerstein MD. Limitations. Patients were evaluated objectively using the Manchester Scar Scale at the end of treatment. In response to injury, tough collagen fibers are produced on the skin’s surface to knit the damaged area closed in order to allow healing. As we mentioned above, gel prepared with onion extracts can make … 0 How to make and use: Peel the onion and wash it thoroughly. Effect of Mederma on hypertrophic scarring in the rabbit ear model. A visual analogue scale (VAS) was also used to quantify the overall scar appearance on a range of 0 to 10 (with the highest number indicating the worst appearance). Step 1: Use silicone gel Apply silicone gel or sheets to scars. Always use onion extract, alone or in a topical product, under the supervision of your dermatologist. Place a coffee filter over the opening of the second beaker and pour the onion mixture into it. According to a survey conducted in 2009, topical onion extract gel is commonly used in commercial antiscar medications.3 Its active component, Allium cepa, demonstrates anti-inflammatory, antiproliferative, antibacterial, and fibrinolytic properties.4,5. Moreover, this extract is very effective on hypertrophic and keloid scars (scars that come from a surgery or injury). We designed a prospective, interventional, comparative, double-blind case series involving patients who underwent upper blepharoplasty. leaves an opening in the dermis. Chop it into small cubes. Zoe Diana Draelos MD. Scars occur when any damage to the skin from wounds, acne, disease, chickenpox, etc. Draelos ZD. This might explain the discrepancies between the results of our study and these studies. Effectiveness of onion extract gel on surgical scars in asians. Weeks and the remaining 15 people will not receive any treatment. We compared the scores of the two observers, which showed no significant difference (p-value: 0.719), and used the average for the final comparison. Dice the onion into small pieces of uniform size and place them in one of the beakers. You will need a cutting board and sharp knife to prepare the onion. All of them were Iranian women. It will smash the vegetable by putting force on it and extract the juice completely. Place the beaker in a water bath at 140 degrees Fahrenheit for 15 minutes. Saulis AS, Mogford JH, Mustoe TA. Ingredients in Mederma Gel Water (Purified), PEG-4, Allium Cepa (Onion) Bulb Extract, Xanthan Gum, Allantoin, Fragrance, Methylparaben, Sorbic Acid This suggests that onion extract gel might be effective for anatomical regions with a thickened dermis that are considered high-risk for scar formation. The final follow-up took place by phone in the sixth postoperative month. The lesions were removed with a scalpel shave, following local anesthesia with 2% lidocaine plus epinephrine. Another option for how to get rid of scars is silicone gel sheeting. Onion In Scar Cream: How It Works. Further studies are needed to confirm our findings. Now I can see why some scar treatment makers, such as Invicible, go out of their way to say they don’t use onion extract. Dermatol Surg. Pilot study evaluating topical onion extract as treatment for postsurgical scars. Measurements.The Manchester Scar Scale evaluates five different characteristics of scar: color (score: 1–4), distortion (score: 1–4), contour (score: 1–4), texture (score: 1–4), and transparency (score: 1–2). One of these 11 patients completed the follow-up, and 10 cases left the study early because of intolerable symptoms. The results revealed no significant disparities between the two scar sites on the basis of subjectivity (p-value: 0.763). The participants enrolled in this prospective, double-blind study were randomly treated with either topical onion extract gel or petroleum jelly. Press the flat end that once attached to the root to the top of the fine side of the grater. In this study, we compared the effectiveness of a topical onion extract gel (Contractubex; Merz Pharmaceuticals, Frankfurt, Germany) with petroleum jelly for the improvement of blepharoplasty scars. Testing has been conducted with 30 participants with keloid scars. Search for more papers by this author. There was no statistically significant difference between two sides (p-value: 0.25). Mederma Scar Removal Cream shows great results in treating many types of scars – acne scars, surgery scars, scars from burns, cuts, wounds, and other injuries. The aim of this study is to evaluate the effectiveness of onion extract gel in improving the cosmetic and symptoms of surgical scars in Asians. The European formulation used in this study ((Contractubex®) contains Allium cepa, allantoin, and heparin, the latter of which is thought to inhibit fibroblast proliferation.9  The manufacturers of these onion extract agents have claimed their products cosmetically improve surgical scarring,10 but the clinical efficacy in scar improvement has not been shown.8, The exact mechanism of onion extract in the wound healing process is unknown.